Journal of the American College of Cardiology Background Although recommended in guidelines for the management of coronary heart disease (CHD), concerns have been raised about the applicability of evidence from existing meta-analyses of exercise-based cardiac rehabilitation (CR). Objectives The goal of this study is to update the Cochrane systematic review and meta-analysis of exercise-based CR for
The American Journal of Cardiology Takotsubo cardiomyopathy (TC) often occurs after emotional or physical stress. Norepinephrine levels are unusually high in the acute phase, suggesting a hyperadrenergic mechanism. Comparatively little is known about parasympathetic function in patients with TC. We sought to characterize autonomic function at rest and in response to physical and emotional stimuli
Aldosterone Predicts Cardiovascular, Renal, and Metabolic Disease in the General Community: A 4‐Year Follow‐Up
Abstract Background We recently reported that normal aldosterone levels are associated with cardiovascular, renal, and metabolic disease in a sample of the US general community (Visit 1). For the current analyses we used the same cohort in a new 4‐year follow‐up study (Visit 2). Methods and Results We measured aldosterone at Visit 1 and analyzed
Blood pressure lowering for prevention of cardiovascular disease and death: a systematic review and meta-analysis
Summary Background The benefits of blood pressure lowering treatment for prevention of cardiovascular disease are well established. However, the extent to which these effects differ by baseline blood pressure, presence of comorbidities, or drug class is less clear. We therefore performed a systematic review and meta-analysis to clarify these differences. Method For this systematic review
Amazing! A new vaccine can significantly reduce low-density lipoprotein (LDL) cholesterol (the bad one) in both mice and rhesus macaque monkeys. The study comes from some researchers led by Dr. Bryce Chackerian of the Department of Molecular Genetics and Microbiology at the University of New Mexic and has been published in the scientific journal
Comparative Performance of ATRIA, CHADS2, and CHA2DS2-VASc Risk Scores Predicting Stroke in Patients With Atrial Fibrillation
The authors of this study evaluated the effectiveness of CHA2DS2-VASc and CHADS2 scores compared with ATRIA score for predicting stroke risk in 60,594 patients with atrial fibrillation not on warfarin. The ATRIA score had a C statistic of 0.70, which was slightly higher than the C statistic of 0.68 for both the CHADS2 and CHA2DS2-VASc
A Summary of 2015 AHA Guidelines Update for CPR and Emergency Cardiovascular Care CARDIOPULMONARY RESUSCITATION Based on the 2015 American Heart Association (AHA) Guidelines Update for Cardiopulmonary Resuscitation (CPR) and Emergency Cardiovascular Care (ECC)1 Key Points • The guidelines are an update to the 2010 AHA Guidelines for CPR and ECC, incorporating evidence from systematic
Una metanalisi pubblicata da Lancet Oncology aveva evidenziato un possibile modesto aumento di rischio di sviluppare neoplasie nei pazienti in terapia con sartani. Dopo il commento di Mauro Venegoni del Centro regionale Farmacovigilanza di Milano, diamo spazio ai professori Massimo Volpe e Alberto Morganti che espongono la posizione della Società Italiana di Ipertensione Arteriosa.
La terapia con fibrati o statine può aumentare il rischio di sanguinamento GI nei soggetti in trattamento con warfarin
di Michelle Rizzo- Medscape-cardiology-news Initiation of a fibrate or statin that inhibits CYP3A4 enzymes -- including fenofibrate, gemfibrozil, fluvastatin, simvastatin, and atorvastatin -- increases the risk of hospitalization for GI bleeding in chronic warfarin users, according to a report in the February issue of the American Journal of Medicine.